Psychedelic Science 2023

Be Part of

        the Breakthrough

Presented by

Molecular and neuronal responses to psychedelic-induced plasticity

PS2023-196-tn

Molecular and neuronal responses to psychedelic-induced plasticity

A single dose of psychedelics robustly yet transiently elevates neural activity, leads to a large-scale engagement of neural plasticity, and may provide immediate and enduring relief from treatment-resistant depression, end-of-life anxiety, or withdrawal symptoms in addiction. We focus on the multiple neuron types that mediate excitatory or inhibitory activity in the prefrontal cortex and address the lack of a high-resolution, genome-wide understanding of how psychedelics induce plasticity in distinct cell types at the transcriptomic level. In parallel, we measure how psychedelics induce long-lasting plasticity in select cell types in the prefrontal cortex at the physiological level. By explicitly addressing the relationship between intrinsic and synaptic plasticity, we assess how a large-scale plasticity event induced by psychedelics does not destabilize neural networks but instead induces cognitive flexibility.

Share: Molecular and neuronal responses to psychedelic-induced plasticity

Facebook
Twitter
LinkedIn
Email

Already Registered?

If you already registered for the in-person portion of the Psychedelic Science 2023 conference, get immediate access to PS2023: The Virtual Trip by logging in with the email address you used when signing up for the conference. We’ll email you a login link—no password necessary!

Need to Register?

If you are not yet registered for Psychedelic Science 2023, you can sign up for PS2023: The Virtual Trip access by creating an account.